Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.3
USERS' SCORE
Good
Based on 3 Reviews
8.4
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Lutein (Free Lutein)(From Lutein Esters)(From Marigold Flowers Extract) (Tagetes erecta)
20 mg
*

Top Medical Research Studies

8
Carotenoids linked to heart health
We explored the relationship between serum levels of carotenoids, like lutein, and cardiovascular-kidney-metabolic syndrome in over 1,600 U.S. adults. Through extensive analysis, we found that higher lutein levels corresponded with a lower likelihood of advanced CKM syndrome. Other carotenoids also showed similar protective effects, but β-cryptoxanthin did not demonstrate any significant benefit. This suggests that increasing intake of carotenoids, especially lutein, may be a smart choice for heart health.
Read More
We aimed to investigate how levels of certain carotenoids impact mortality rates in adults with metabolic dysfunction-associated fatty liver disease (MAFLD). Our analysis involved over 3,000 participants and focused on deaths from all causes, including cardiovascular issues.

Interestingly, higher levels of lutein and other carotenoids correlated with a lower risk of death. Specifically, those with the highest lutein levels were 38% less likely to die from cardiovascular disease compared to those with the lowest levels. However, it's important to note that while the correlation exists, we cannot definitively claim that lutein directly prevents heart disease based on this study alone.
Read More
8
Supplementation reduces inflammation markers
In our double-blind, placebo-controlled study, we assessed the effects of lutein, zeaxanthin, and meso-zeaxanthin on cardiovascular inflammation and oxidative processes. Participants received either the active supplement or a placebo for six months.

We found significant reductions in key inflammatory markers and oxidized LDL in those taking the supplement. These results suggest that lutein and its companions may help combat inflammation, potentially contributing to healthier cardiovascular systems by supporting lower levels of harmful lipid oxidation.
Read More

Most Useful Reviews

7.5
Eases visual fatigue
1 people found this helpful
I spend the entire day at the computer, but since I began consuming this, I can see clearly even in the afternoon when I'm weary, and I have noticed that my fatigue and dry eyes have improved.
Read More
9
Improves eyesight
This is not my first purchase, and it genuinely enhances eyesight while providing support for eye diseases! I will continue to take it.
Read More
7.5
Protects against diseases
Lutein is a potent antioxidant that offers numerous health benefits. It safeguards the eyes from free radicals and UV damage, effectively reducing the risk of vision deterioration. Additionally, it enhances contrast perception and night vision. Lutein also has protective qualities for eye health, aiding in the prevention of eye conditions like cataracts and macular degeneration. Furthermore, it benefits skin health by minimising damage from UV rays and oxidative stress.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.3
  • All Researches
9
Lutein improves mitochondrial function
We explored the potential of lutein, a powerful antioxidant, in treating myocardial ischemia-reperfusion injury. To enhance its effectiveness, a novel delivery system named lutein@DTPP was developed, allowing for targeted administration directly to heart tissues.

Our findings showed that this method improved mitochondrial function in heart cells, crucial for reducing damage and preventing cell death. However, while lutein demonstrated benefits in this context, it's important to note that the study primarily focused on a specific injury model, and broader effects on cardiovascular disease might still require more investigation.
Read More
8
Carotenoids linked to heart health
We explored the relationship between serum levels of carotenoids, like lutein, and cardiovascular-kidney-metabolic syndrome in over 1,600 U.S. adults. Through extensive analysis, we found that higher lutein levels corresponded with a lower likelihood of advanced CKM syndrome. Other carotenoids also showed similar protective effects, but β-cryptoxanthin did not demonstrate any significant benefit. This suggests that increasing intake of carotenoids, especially lutein, may be a smart choice for heart health.
Read More
We aimed to investigate how levels of certain carotenoids impact mortality rates in adults with metabolic dysfunction-associated fatty liver disease (MAFLD). Our analysis involved over 3,000 participants and focused on deaths from all causes, including cardiovascular issues.

Interestingly, higher levels of lutein and other carotenoids correlated with a lower risk of death. Specifically, those with the highest lutein levels were 38% less likely to die from cardiovascular disease compared to those with the lowest levels. However, it's important to note that while the correlation exists, we cannot definitively claim that lutein directly prevents heart disease based on this study alone.
Read More
8
Supplementation reduces inflammation markers
In our double-blind, placebo-controlled study, we assessed the effects of lutein, zeaxanthin, and meso-zeaxanthin on cardiovascular inflammation and oxidative processes. Participants received either the active supplement or a placebo for six months.

We found significant reductions in key inflammatory markers and oxidized LDL in those taking the supplement. These results suggest that lutein and its companions may help combat inflammation, potentially contributing to healthier cardiovascular systems by supporting lower levels of harmful lipid oxidation.
Read More
8
Carotenoid intake reduces AAC risk
Our analysis focused on how carotenoid intake relates to abdominal aortic calcification (AAC), a crucial indicator of cardiovascular risk. In a study with 2,889 participants, we found that increased consumption of carotenoids—particularly lutein and zeaxanthin—was linked to a reduced risk of severe AAC.

Results showed that higher intakes of various carotenoids, including lutein, significantly lowered the odds of AAC, emphasizing the potential heart health benefits of these nutrients. This suggests that including more carotenoid-rich foods in our diet might be beneficial for our cardiovascular health.
Read More

User Reviews

USERS' SCORE
Good
Based on 3 Reviews
8.4
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
Eases visual fatigue
1 people found this helpful
I spend the entire day at the computer, but since I began consuming this, I can see clearly even in the afternoon when I'm weary, and I have noticed that my fatigue and dry eyes have improved.
Read More
9
Improves eyesight
This is not my first purchase, and it genuinely enhances eyesight while providing support for eye diseases! I will continue to take it.
Read More
7.5
Protects against diseases
Lutein is a potent antioxidant that offers numerous health benefits. It safeguards the eyes from free radicals and UV damage, effectively reducing the risk of vision deterioration. Additionally, it enhances contrast perception and night vision. Lutein also has protective qualities for eye health, aiding in the prevention of eye conditions like cataracts and macular degeneration. Furthermore, it benefits skin health by minimising damage from UV rays and oxidative stress.
Read More

Frequently Asked Questions

7.5
Eases visual fatigue
1 people found this helpful
I spend the entire day at the computer, but since I began consuming this, I can see clearly even in the afternoon when I'm weary, and I have noticed that my fatigue and dry eyes have improved.
9
Improves eyesight
This is not my first purchase, and it genuinely enhances eyesight while providing support for eye diseases! I will continue to take it.
7.5
Protects against diseases
Lutein is a potent antioxidant that offers numerous health benefits. It safeguards the eyes from free radicals and UV damage, effectively reducing the risk of vision deterioration. Additionally, it enhances contrast perception and night vision. Lutein also has protective qualities for eye health, aiding in the prevention of eye conditions like cataracts and macular degeneration. Furthermore, it benefits skin health by minimising damage from UV rays and oxidative stress.
8
Lutein may lower heart disease risk
We examined the effects of serum carotenoids, specifically lutein, on cardiovascular disease (CVD) risk using a robust data set from the National Health and Nutrition Examination Survey.

Our analysis of over 12,000 participants revealed that higher levels of lutein were linked to a lower prevalence of CVD, including a significant reduction in risks of heart attack and stroke.

Although lutein shows promise, it’s essential to remember that these findings indicate correlation, not causation, and we can't say for certain that lutein directly prevents heart disease.
8
Supplementation reduces inflammation markers
In our double-blind, placebo-controlled study, we assessed the effects of lutein, zeaxanthin, and meso-zeaxanthin on cardiovascular inflammation and oxidative processes. Participants received either the active supplement or a placebo for six months.

We found significant reductions in key inflammatory markers and oxidized LDL in those taking the supplement. These results suggest that lutein and its companions may help combat inflammation, potentially contributing to healthier cardiovascular systems by supporting lower levels of harmful lipid oxidation.
9
Lutein improves mitochondrial function
We explored the potential of lutein, a powerful antioxidant, in treating myocardial ischemia-reperfusion injury. To enhance its effectiveness, a novel delivery system named lutein@DTPP was developed, allowing for targeted administration directly to heart tissues.

Our findings showed that this method improved mitochondrial function in heart cells, crucial for reducing damage and preventing cell death. However, while lutein demonstrated benefits in this context, it's important to note that the study primarily focused on a specific injury model, and broader effects on cardiovascular disease might still require more investigation.
We aimed to investigate how levels of certain carotenoids impact mortality rates in adults with metabolic dysfunction-associated fatty liver disease (MAFLD). Our analysis involved over 3,000 participants and focused on deaths from all causes, including cardiovascular issues.

Interestingly, higher levels of lutein and other carotenoids correlated with a lower risk of death. Specifically, those with the highest lutein levels were 38% less likely to die from cardiovascular disease compared to those with the lowest levels. However, it's important to note that while the correlation exists, we cannot definitively claim that lutein directly prevents heart disease based on this study alone.
We investigated how serum carotenoids, including lutein, relate to cardiovascular mortality in hypertensive adults. Analyzing data from nearly 8,400 participants, we observed that higher levels of various carotenoids were associated with a reduced risk of all-cause mortality.

However, our findings showed that while certain carotenoids linked with lower cardiovascular mortality, lutein and β-carotene did not demonstrate a significant protective effect. This suggests that while carotenoids may be beneficial, not all types provide the same level of cardiovascular protection.

References

  1. Sun L, He Z, Li Y, Huo Z, Liu L. The relationship between nutrient intake, lifestyle, and non-alcoholic fatty liver disease in patients with type 2 diabetes mellitus: Results from the National Health and Nutrition Examination Surveys 2007-2018. Clin Nutr ESPEN. 2025;66:446. doi:10.1016/j.clnesp.2025.02.008
  2. Li C, Liang Y, Lu Q, Lin Y, Wen S, et al. Protective effect of serum carotenoids on mortality among metabolic syndrome patients: attenuated by lipid-lowering drugs. Nutr J. 2025;24:27. doi:10.1186/s12937-025-01092-x
  3. Chen M, Cai S, Jia Q, Suo Y, Tang Y, et al. Inverse Relationship Between Serum Carotenoid Levels and Cardiovascular-Kidney-Metabolic Syndrome Among the General Adult Population. J Diabetes. 2025;17:e70046. doi:10.1111/1753-0407.70046
  4. Shi P, Sha Y, Wang X, Yang T, Wu J, et al. Targeted Delivery and ROS-Responsive Release of Lutein Nanoassemblies Inhibit Myocardial Ischemia-Reperfusion Injury by Improving Mitochondrial Function. Int J Nanomedicine. 2024;19:11973. doi:10.2147/IJN.S488532
  5. Lin B, Liu Z, Li D, Zhang T, Yu C. Associations of serum carotenoids with all-cause and cardiovascular mortality in adults with MAFLD. Nutr Metab Cardiovasc Dis. 2024;34:2315. doi:10.1016/j.numecd.2024.06.001
  6. Stringham NT, Green M, Roche W, Prado-Cabrero A, Mulcahy R, et al. Lutein, zeaxanthin, and meso-zeaxanthin supplementation attenuates inflammatory cytokines and markers of oxidative cardiovascular processes in humans. Nutr Metab Cardiovasc Dis. 2024;34:1976. doi:10.1016/j.numecd.2024.05.009
  7. Masle AM, Kibel A, Jukić I, Čičak P, Selthofer-Relatić K, et al. Enhancing Endothelial Function with Nutrient-Enriched Table Hen Eggs: A Randomized Study in Patients Recovering from Acute Coronary Syndrome. Clin Interv Aging. 2024;19:953. doi:10.2147/CIA.S461821
  8. Chen W, Li Y, Li M, Li H, Chen C, et al. Association between dietary carotenoid intakes and abdominal aortic calcification in adults: National Health and Nutrition Examination Survey 2013-2014. J Health Popul Nutr. 2024;43:20. doi:10.1186/s41043-024-00511-9
  9. Kolar L, Šušnjara P, Stupin M, Stupin A, Jukić I, et al. Enhanced Microvascular Adaptation to Acute Physical Stress and Reduced Oxidative Stress in Male Athletes Who Consumed Chicken Eggs Enriched with n-3 Polyunsaturated Fatty Acids and Antioxidants-Randomized Clinical Trial. Life (Basel). 2023;13. doi:10.3390/life13112140
  10. Ba W, Xu W, Deng Z, Zhang B, Zheng L, et al. The Antioxidant and Anti-Inflammatory Effects of the Main Carotenoids from Tomatoes via Nrf2 and NF-κB Signaling Pathways. Nutrients. 2023;15. doi:10.3390/nu15214652
  11. Wang M, Tang R, Zhou R, Qian Y, Di D. The protective effect of serum carotenoids on cardiovascular disease: a cross-sectional study from the general US adult population. Front Nutr. 2023;10:1154239. doi:10.3389/fnut.2023.1154239
  12. Šušnjara P, Mihaljević Z, Stupin A, Kolobarić N, Matić A, et al. Consumption of Nutritionally Enriched Hen Eggs Enhances Endothelium-Dependent Vasodilation via Cyclooxygenase Metabolites in Healthy Young People-A Randomized Study. Nutrients. 2023;15. doi:10.3390/nu15071599
  13. Zhu X, Cheang I, Tang Y, Shi M, Zhu Q, et al. Associations of Serum Carotenoids With Risk of All-Cause and Cardiovascular Mortality in Hypertensive Adults. J Am Heart Assoc. 2023;12:e027568. doi:10.1161/JAHA.122.027568
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